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#BASIC IMMUNOLOGY ABBAS CHAPTER 1 2 FULL#
The first chap- ter introduces the immune system, with photographs of cells and organs of the immune system, beautiful drawings, graphs, and tables.Īnybody who finds the current field incomprehensible should study this chapter it is bound to leave the reader with a full appreciation of modern immunology.
Nothing in this book seems to have been done just for the sake of it, and the precious whole is presented as a handy package. The book ends with a list of suggested readings (carefully selected except for the reference to the 1993 map of the human major histocompatibility complex (MHC) which is now updated by the report of the MHC Sequencing Consortium in Nature, 1999 401:921) and three appendices containing 1) a list of known CD molecules, 2) a 24-page glossary, and 3) five clin- ical cases with questions and answers. The plain language, coupled with the unin- timidating size of the book, relieves the apprehensive reader at the outset.Ībundant diagrams, figures, charts, and tables make it easier to follow the subject.Įven the text is frequently decorated with sections in boldface type to emphasize key concepts so that by just skim- ming through the pages and reading only those highlighted sections one can get a quick sense of basic immunology in minutes.Įach chapter is summarized in bullet form with accompanying review questions. T oday s immunology, at its current level of complexity, could not be put into 232 pages of text in a more comprehensive, yet accessible, way. It will also serve researchers with little training in immunology well. Saunders Company, Philadelphia, Pennsylvania (Telephone: 2152387800 Fax: 2152387883), 2001, 309 pp., 43.95 Having already produced a now classic immunology text- book (1), Abbas and Lichtman have done another good job in preparing this book primarily for students and others with lit- tle or no background in immunology. V accine theory of AIDS origins disputed at Royal Society.īasic Immunology: Functions and Disorders of the Immune System Abul K.ī. The river: a journey to the source of HIV and AIDS.Ĭohen J. Subsequently, a report in Science provided detailed data on the molecular analyses of coded samples of the imputed OPV and control materials (3).Ĭonfirming the earlier pre- liminary reports, no evidence was found for the presence of chimpanzee DNA in the OPV samples, although monkey DNA was identified. Hilary Koprowski and her colleagues, who had produced the vaccine, had consistently maintained that only monkey kidney cells had been used to produce it. Preliminary reports indicated that all samples tested negative for SIV and human immunodeficiency virus and positive for mitochondrial DNA from monkeys, but not from chimpanzees.
Of particular relevance were representatives of three laboratories that had been studying the molecular biology of remaining samples of the vaccine. That meeting brought together a number of acquired immunodeficiency virus researchers as well as vet- eran participants in the OPV trials. The Royal Society meet- ing was described in an article in the journal Science last year (2). Monto men- tioned, but did not elaborate on, a 2-day meeting of the Royal Society in London and recent reports that should have negated Hoopers allegations. Readers will recall that Monto effectively debunked author Edward Hoopers thesis that human immunodeficiency virus had entered the human population either by use of or contami- nation by simian immunodeficiency virus (SIV)cpz-infected cells from W est African chimpanzees allegedly used in an experimental oral poliovirus vaccine (OPV) tested in more than a million W est Africans during the 1950s. These 18 pages introduce the reader to the cells of the innate immune system, chemokines, cytokines, and complement molecules as well.
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